Table of Contents
Where It Comes From
Alpha GPC (Alpha-glycerylphosphorylcholine) is a naturally occurring choline compound found in the brain. It is a precursor of acetylcholine, a neurotransmitter involved in memory formation, learning, and cognitive function. Dietary supplements widely use Alpha GPC to promote brain health and cognitive performance, generating it from soy lecithin and other sources. It is well-known for its ability to cross the blood-brain barrier, making it extremely effective in delivering choline directly to the brain.
What It is Indicated For
People typically take Alpha GPC to improve memory, cognitive function, and concentration. It is popular among people looking to improve their mental clarity, learning ability, and overall brain health. Sports nutrition also utilizes Alpha-GPC due to its capacity to enhance power output and facilitate muscle recovery, as acetylcholine plays a crucial role in muscle contraction.
Key Benefits:
- Memory Enhancement: Research has proven that Alpha GPC enhances memory, particularly in individuals experiencing age-related cognitive decline. Clinical Therapeutics published a study that found Alpha-GPC supplementation significantly improved cognitive function and memory in patients suffering from Alzheimer’s disease and vascular dementia.
- Cognitive Function: Alpha GPC improves cognitive function by raising acetylcholine levels in the brain, which helps with learning, attention, and mental clarity. The Journal of the International Society of Sports Nutrition published a study that found Alpha-GPC supplementation enhanced cognitive performance in healthy adults, especially in stressful environments.
- Focus and Mental Clarity: Alpha GPC is known for its ability to promote focus and mental clarity, making it useful for tasks that require long-term attention and cognitive stress. A study published in Nutritional Neuroscience found that Alpha GPC increased cognitive function and reduced mental tiredness in a group of young people.
Contraindications
Most people typically find Alpha GPC safe, but those with hypotension (low blood pressure) or those on blood pressure-lowering medications should use it with caution as it may further lower blood pressure. Pregnant or breastfeeding women should see their doctor before using Alpha-GPC.
Warnings
Most people tolerate Alpha GPC well, although some may develop moderate side effects such as headaches, dizziness, or stomach discomfort, especially at higher doses. It is critical to follow the prescribed dosage on the product label and consult with a healthcare expert if you have any concerns or pre-existing medical conditions.
Dosages
The normal Alpha GPC dosage is between 300 and 600 mg per day, depending on the intended impact and individual requirements. Clinical studies frequently utilize doses in this range to obtain cognitive advantages and increase mental function while avoiding substantial negative effects. Typically, researchers suggest a daily dose of 300 mg for cognitive enhancement, but athletes may need higher doses to enhance their physical performance.
Products Contained In
Alpha Brain: A popular nootropic that contains Alpha GPC to improve focus, memory, and mental clarity.
NooCube: A cognitive enhancement supplement featuring Alpha GPC to support brain health and improve cognitive function.
Qualia Mind: A high-potency nootropic that uses Alpha GPC to boost memory, focus, and overall cognitive performance.
Genius Consciousness: A cognitive enhancement formula that includes Alpha GPC for its focus-boosting and brain health benefits.
References
1. Parnetti, L., Abler, A., & Ferris, S. (2001). A multi-center, double-blind, randomized, controlled trial of alpha-glycerylphosphorylcholine to treat cognitive impairment in Alzheimer’s disease. Clinical Therapeutics, 23(11), 1855–1874.
2. Bellar, D., LeBlanc, N. R., & Campbell, B. (2015). The effect of alpha-glycerylphosphorylcholine on isometric strength and psychomotor function. Journal of the International Society of Sports Nutrition, 12(1):20.
3. Rai, N., & Thorat, V. (2013). Alpha-GPC as a choline source and its cognitive enhancement properties: A review. Nutritional Neuroscience, 16(2), 89–98.
