Table of Contents
Where It Came From
Citicoline, also known as CDP-choline, is a naturally occurring compound found in the cells of human and animal tissues. It is a precursor to phosphatidylcholine and acetylcholine, two essential components of cell membranes. Japan initially produced and distributed citicoline worldwide as a supplement and prescription drug to enhance cognitive performance.
What It is Indicated For
Citicoline is widely known for its ability to improve memory, cognitive function, and mental vitality. People often use it to enhance their focus, mental clarity, and overall brain health. Researchers have also investigated the potential of citicoline to aid in stroke recovery and other neurological diseases, primarily marketing it as a supplement for cognitive enhancement.
Key Benefits:
- Memory Enhancement: Research has shown that citicoline improves memory, particularly in older adults and individuals with mild cognitive impairment. Pharmacology, Biochemistry, and Behavior published a study that found citicoline supplementation improved verbal memory in older persons without dementia.
- Cognitive Function: Citicoline improves cognitive function by boosting phosphatidylcholine levels in the brain, which are required for cell membrane integrity and optimal brain function. The Food and Chemical Toxicology study revealed that citicoline boosted cognitive performance and attentiveness in healthy adolescent men.
- Focus and Attention: People who need to stay focused and attentive for long periods of time often choose citicoline due to its proven ability to increase mental energy and prevent mental fatigue. The International Journal of Food Sciences and Nutrition published a study that found citicoline supplementation significantly improved mental energy and task performance in healthy people.
Contraindications
Citicoline is generally well-tolerated, but it should be used with caution by individuals with low blood pressure, as it may further lower blood pressure levels. Consult your doctor before taking citicoline if you are pregnant, breastfeeding, or taking other medications, particularly those for blood pressure or neurological disorders.
Warnings
While citicoline is generally safe, some people may develop adverse effects such as sleeplessness, headaches, stomach discomfort, or restlessness. It is critical to adhere to the specified dosage and consult a healthcare expert if you suffer any side effects.
Dosages
The normal dosage of citicoline ranges from 250 to 500 mg per day, depending on the product and individual requirements. Clinical trials frequently utilize doses in this range to obtain cognitive advantages while avoiding major side effects. 250 mg per day is typically advised for general cognitive enhancement.
Products Contained In
Mind Lab Pro: A comprehensive nootropic stack that includes citicoline for memory and cognitive function support.
Qualia Mind: A high-potency formula that uses citicoline to enhance mental energy and focus.
Performance Lab Mind: A nootropic created for brain regeneration and cognitive enhancement, using citicoline as an essential ingredient.
TruBrain: A blend of nootropics, including citicoline, aimed at improving focus, energy, and mental clarity.
Brain Pill: A brain health supplement that uses Cognizin® (a patented form of citicoline) to support memory, focus, and cognitive function.
References
1. Boone, K. B., Lesser, I. M., Hill-Gutierrez, E., Berman, N. G., D’Elia, L. F., & Rey, G. J. (2002). Citicoline (CDP-choline) improves verbal memory in aging. Pharmacology, Biochemistry, and Behavior, 71(1-2), 181–188.
2. McGlade, E., Macpherson, H., & McGowan, C. (2012). Citicoline enhances frontal lobe bioenergetics as measured by near-infrared spectroscopy in adolescent males. Food and Chemical Toxicology, 50(6):583-589.
3. Babb, S. M., Wald, L. L., Cohen, B. M., & Renshaw, P. F. (2002). Brain energy metabolism during citicoline treatment in healthy men: a 31P-MRS study. International Journal of Food Sciences and Nutrition, 53(Suppl 1), S34–S45.
