Table of Contents
Where It Comes From
Dimethylaminoethanol (DMAE) is an organic compound with structural similarities to choline, a precursor to the neurotransmitter acetylcholine, which is essential for memory and learning. DMAE is present in trace amounts in the human brain and certain types of fish, including anchovies and sardines. Supplements have utilized it for its potential cognitive-enhancing and anti-aging benefits.
What It is Indicated For
People generally use DMAE to improve cognitive function, memory retention, and mental clarity. It is also renowned for its ability to improve mood, alleviate symptoms of depression, and improve focus. Moreover, DMAE is believed to possess anti-aging properties, particularly in enhancing skin tone and diminishing the visibility of fine lines and wrinkles, but its primary application lies in supplements aimed at enhancing cognitive function.
Key Benefits of DMAE:
- Cognitive Enhancement: Researchers believe that DMAE enhances cognitive performance by boosting the production of acetylcholine, a neurotransmitter that supports memory, learning, and overall brain function. The journal Psychopharmacology published a study that found DMAE supplementation enhanced mental alertness and focus in healthy individuals.
- Memory Support: DMAE may improve memory by increasing the synthesis of acetylcholine, a neurotransmitter required for memory formation and retrieval. The Journal of the American Geriatrics Society published a study that found DMAE supplementation enhanced memory and cognitive performance in older persons with mild cognitive impairment.
- Mood and Focus: Research has shown that DMAE enhances mood and focus by regulating critical neurotransmitters in the brain, including acetylcholine and dopamine. Research in Psychopharmacologia found that DMAE reduced depression symptoms and enhanced mood in those with emotional disorders.
Contraindications
DMAE is usually regarded as safe for most people; however, persons with epilepsy or seizure disorders should exercise caution because it may increase the chance of seizures. Furthermore, persons with bipolar disorder or other psychiatric illnesses should visit a doctor before using DMAE, as it may worsen symptoms in some circumstances. Pregnant or breastfeeding women should avoid DMAE due to insufficient safety data.
Warnings
Most people tolerate DMAE well; however, some may develop moderate side effects such as headaches, insomnia, muscle tension, or gastrointestinal discomfort, especially at larger doses. It is critical to follow the prescribed dosage on the product label and consult with a healthcare expert if you have any concerns or pre-existing medical conditions.
Dosages
The normal DMAE dosage ranges between 100 and 300 mg per day, depending on the intended impact and individual requirements. Clinical trials frequently employ doses in this range to obtain cognitive and mood-enhancing benefits with minimal side effects. For cognitive enhancement and emotional support, a daily dose of 150-300 mg is usual.
Products Contained In
Neuro-Peak: A brain health supplement containing DMAE that promotes memory, focus, and cognitive performance.
References
1. Simpson, C. W., & Stern, M. (1971). Effects of 2-dimethylaminoethanol (Deanol) on humans. Psychopharmacologia, 22(2), 111–117.
2. Crook, T. H., & Tinklenberg, J. R. (1977). Effects of Deanol on memory in elderly humans. The Journal of the American Geriatrics Society, 25(6): 241-244.
3. Russell, R. W., & Langs, L. J. (1975). The effects of 2-dimethylaminoethanol on mental function in humans. Psychopharmacology, 44(3), 205–207.
