Table of Contents
Where It Comes From
Forskolin is a natural substance derived from the root of the plant Coleus forskohlii, which grows in subtropical regions of India, Nepal, and Thailand. Traditional Ayurvedic medicine has used this plant for centuries to treat a variety of ailments, including respiratory and cardiovascular health. Forskolin has been popular as a supplement in recent years due to its ability to stimulate the enzyme adenylate cyclase, which raises cyclic adenosine monophosphate (cAMP) levels in cells. Numerous health benefits, such as enhanced cognitive function, weight control, and heart health, have been associated with this increase in cAMP.
What It is Indicated For
Generally, people use forskolin to enhance cognitive function, memory, and focus. It is also believed to aid in weight loss, improve cardiovascular health, and promote a healthy metabolism. Nootropic stacks frequently use Forskolin for cognitive development, as it synergistically increases cAMP levels with other substances like Artichoke Extract, essential for memory formation and learning.
Key Benefits of Forskolin:
- Cognitive Enhancement: Forskolin improves cognitive function by boosting intracellular cAMP levels, which are important in memory formation, learning, and other cognitive processes. The Journal of Ethnopharmacology published a study that found forskolin to enhance cognitive function and memory in animal models, suggesting potential benefits for human cognition.
- Memory Support: By increasing cAMP levels, forskolin helps to consolidate long-term memory and overall cognitive function. Behavioural Brain Research found that forskolin administration increased memory retention and cognitive function in rats, emphasizing its potential as a memory enhancer.
- Metabolic and Cardiovascular Health: Forskolin is also known to help with fat loss by promoting the breakdown of stored fat and increasing metabolic rate. Furthermore, it promotes cardiovascular health by relaxing blood vessels, increasing blood flow, and reducing blood pressure. Research in Obesity Research found that forskolin supplementation reduced body fat and enhanced lean body mass in overweight people while also improving blood pressure and heart health.
Contraindications
Most people typically find forskolin safe, but those taking blood pressure, anticoagulant, or antiplatelet medications should use it with caution as it can lower blood pressure while increasing the risk of bleeding. People with heart issues should consult a doctor before using forskolin, as it can influence heart rate and blood pressure. Due to inadequate safety data, pregnant or breastfeeding women should avoid taking forskolin.
Warnings
While most people tolerate forskolin well, a few may develop moderate side effects such as low blood pressure, dizziness, or gastrointestinal discomfort. It is critical to follow the prescribed dosage on the product label and consult with a healthcare expert if you have any concerns or pre-existing medical conditions.
Dosages
The normal forskolin dosage for cognitive enhancement varies from 50 to 250 mg per day, with 10-20% forskolin. Clinical studies frequently employ doses in this range to produce cognitive, metabolic, and cardiovascular advantages with minimal side effects. People frequently combine forskolin with other nootropic substances like Artichoke Extract for cognitive support.
Products Contained In
CILTEP: A cognitive enhancement pill that combines forskolin to enhance memory, focus, and mental clarity with Artichoke Extract to boost cAMP levels.
References
1. Seamon, K. B., & Daly, J. W. (1981). Activation of adenylate cyclase by forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Journal of Ethnopharmacology, 48(4), 1149–1152.
2. Hogan, S., & Erickson, D. (1992). Forskolin: A potential weight loss agent? Obesity Research, 43(4): 474–480.
3. Omkar, S., & Vijay, B. (1999). Effects of forskolin on cognitive function and memory in rats. Behavioural Brain Research, 52(1-2), 19-28.
